To create layers in AutoCAD with Python, you can use the Add() method of the Layers collection of the current Document object.

The coding example below creates a new layer and sets its color to red:

import win32com.client

acad = win32com.client.Dispatch("AutoCAD.Application")

# create new layer and change its color
doc = acad.ActiveDocument
layers = doc.Layers
new_layer = layers.Add("newlayer")
new_layer.color = 1

In this example, the Add() method is used to create a new layer with the name “newlayer”. The layer is created via and added to the Layers collection of the AutoCAD document. The color property of the new layer is to 1 (= red color).